Multiple Myeloma (MM)

Sharpen Myeloma Development with Functional and ML Evidence

xCellSense® pairs ex vivo drug sensitivity with machine-learning-based outcome modeling and genomic readouts to support myeloma regimen selection and patient segmentation.

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The MM development challenge

Multiple myeloma involves complex regimen sequencing and selection, deep biological heterogeneity, and increasingly MRD-driven endpoints. The questions are which regimen for which patient and who responds.

What we test in MM

1

Ex vivo drug sensitivity
The response of patient-derived myeloma cells to your asset and comparators

2

ML outcome modeling
Machine-learning models that inform regimen selection and predict response

3

Genomic and biomarker support
Mutation profiling and responder segmentation, with MRD-oriented biomarker workstreams

4

Patient segmentation
Distinct responder subgroups for trial enrichment and companion-diagnostic strategy (research-framed)

Evidence in Multiple Myeloma

Our npj Precision Oncology (2023) study presented a machine-learning sequential model to guide first-line VMP vs. RD selection for 706 newly diagnosed myeloma patients. The platform's myeloma work has also been recognized as an Innovative Medical Device in Korea and has been extended with an automated MRD analysis algorithm.

Scientific Publications
npj Precision Oncology logo

ML-based sequential analysis to assist selection between VMP and RD for newly diagnosed multiple myeloma

npj Precision Oncology
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Why it de-risks development

Regimen-selection insight, responder enrichment, and an MRD/biomarker strategy grounded in large-cohort modeling.

Key Deliverables

01
Ex vivo drug sensitivity using live patient-derived myeloma cells
02
ML outcome modeling for regimen selection and response prediction
03
Genomic profiling and responder segmentation
04
Interpretation and dataset with a fast turnaround time
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Scope a Myeloma Study

A scientist — not a sales desk — will scope a tailored MM study and return a design and timeline.