The ImpriMed Multidrug Sensitivity Genotyping (MDR1) is a non-invasive and reliable way to determine if a dog has the genetic mutation known as MDR1. This genotyping is particularly important for preventing adverse events in breeds such as Collies, Long-haired Whippets, and Australian Shepherds, but any breed may harbor these mutations. By testing for MDR1 mutations, you can be proactive in avoiding potential adverse reactions and ensuring the safety and well-being of your patients.
The MDR1 gene is responsible for producing a protein that helps eliminate drugs and toxins from the body. Dogs with a mutation in this gene may be unable to eliminate certain drugs effectively, leading to adverse reactions or even toxicity. This can include commonly prescribed anticancer drugs for canine lymphoma such as doxorubicin, vincristine, and vinblastine. See the drugs that may be poorly tolerated by dogs with MDR1 gene mutation here.
Veterinary oncologists can easily order Multidrug Sensitivity Genotyping (MDR1) as an add-on to other ImpriMed services or as a standalone service.
*After the receipt of the sample at the lab in California
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Your patient’s sample analysis is performed in a US laboratory that is accredited to meet A2LA standards. An A2LA-certified lab must meet high standards of quality and ensure the accuracy and reliability of your results. ImpriMed is accredited by A2LA for Canine Lymphoma/Leukemia Clonality Testing by PCR for Antigen Receptor Rearrangements (PARR) and Immunophenotyping by Flow Cytometry.
Collect 2 mL of whole blood in an EDTA-treated tube.
Through your account on our Vet Portal, you can order MDR1 Genotyping as
A standalone service
An add-on to other ImpriMed services
You will receive the MDR1 genotyping results in 2-4 days after we receive the sample.
To get started, fill out the form and we will send pricing to your email.
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