Flow Cytometry + PARR for Feline Lymphoma & Leukemia

Immunoprofile

The ImpriMed Immunoprofile report includes both our complete PARR and flow cytometry testing, as well as an expert interpretation of the results. This combined service includes cell size, clonality, and immunophenotype information that supports an accurate diagnosis of lymphoma and leukemia.

Get cell sizing and immunophenotyping information in 3-4 calendar days*

What's included:

1. PARR (PCR for Antigen Receptor Rearrangement) assay is used to test for B-cell or T-cell clonality, and high-specificity detection of the presence of neoplasia.

2. Flow cytometry
Flow cytometry provides cell-sizing information and analyzes different proteins found on and within tumor cells that denotes immunophenotype. This test provides prognostic information for leukemia and lymphoma.

Sample Collection

For Lymphoma: Collect a biopsy (FNA or tissue) from the affected site(s) into ImpriMed transport tubes. Additionally, collect 2 mL of whole blood in an EDTA-treated tube.
For Leukemia: Collect 2 mL of whole blood in an EDTA-treated tube.

*After the receipt of the sample at the lab in California

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Why should I order the Immunoprofile service instead of stand-alone PARR or Flow Cytometry?

The two tests provide complimentary and different information. PARR has high specificity but lower sensitivity. Flow cytometry has high sensitivity and specificity, but does not enable discrimination between neoplasia and reactive conditions. Together, the two tests enable a more accurate diagnosis.

*After the receipt of the sample at the lab in California

How Does ImpriMed Use Flow Cytometry for cell sizing

For the correct classification of feline lymphoma, two critical factors are paramount: the anatomic form and the size of the lymphocytes. Our new Feline lymphoma/leukemia services enrich your patient care by integrating immunophenotyping and, importantly, precise cell sizing through flow cytometry.

We have developed a novel cell sizing technique using our expertise in flow cytometry and our extensive database of medical records with cytology/histology results from our feline lymphoma research efforts. Flow cytometry is a powerful tool to determine phenotype, cell granularity, and relative cell size. Our method leverages a comprehensive database of medical records and research findings. By comparing flow cytometry results with traditional gold standards (cytology or histology) used in these records, we have defined a method to assess lymphoma cells as small, medium, or large. This approach accurately categorizes lymphocyte size, as validated with an inter-laboratory comparison of our flow cytometry sizing and cytology provided by an accredited diagnostics laboratory.

Our novel cell sizing system for feline lymphoma provides an accurate and reproducible readout of this important characterization parameter for your patient’s lymphocytes.

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Our science sets us apart

Pioneers in AI-driven Drug Response Predictions
We are proud to be at the forefront of the latest advancements in artificial intelligence and veterinary medicine. We take science-forward and data-driven approaches in providing accurate and reliable predictions to help veterinary oncologists make informed treatment decisions. We share your passion for helping cancer patients and take pride in providing you with the best user experience, customer service, and clinical decision support in the industry.

A2LA accredited (Certificate #5664.01)
Your patient’s sample analysis is performed in a US laboratory that is accredited to meet A2LA standards. An A2LA-certified lab must meet high standards of quality and ensure the accuracy and reliability of your results. ImpriMed is accredited by A2LA for Feline Lymphoma/Leukemia Clonality Testing by PCR for Antigen Receptor Rearrangements (PARR) and Immunophenotyping by Flow Cytometry.

How It WOrks

Illustration of a mailer box filled with ImpriMed's proprietary transport media tubes
1. Request Media Tubes

Fill out the form below to request media tubes. And register on our Vet Portal to order our services.

Illustration of a mailer box filled with ImpriMed's proprietary transport media tubes
2. Collect FNA & Blood Samples

Collect a biopsy (FNA or tissue) from the affected site(s) into ImpriMed transport tubes. Additionally, collect 2 mL of whole blood in an EDTA-treated tube.

Guide to sampling: Watch video here

3. Order Service & Ship Samples

Through your account on our Vet Portal, select services needed. Make sure you provide information about your patient and samples on our online portal. Pack the collected samples (FNA and blood) with ice packs and then ship them to ImpriMed using the boxes and FedEx labels provided.

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4. Check Your Email

The final report is emailed to the ordering veterinarian in 3-4 calendar days via secure email.

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Try ImpriMed

To get started, fill out the form and we will send our proprietary transport media tubes to your clinic.

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Book a meeting with us

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Frequently asked questions

For Veterinarians

What services does ImpriMed offer?

What does the ImpriMed Personalized Prediction Profile include?

Which drugs are included in the ImpriMed Personalized Prediction Profile?

What is included in the ImpriMed Immunoprofile service?

Why should I order ImpriMed services?

What is a drug sensitivity test?

Which cancers can I use ImpriMed for?

How does ImpriMed predict drug responses?

How long until I get my ImpriMed report?

How do I order an ImpriMed service?

What patient samples are required for ImpriMed services?

How do I collect an FNA sample?

How many cells are needed for each type of service?

What does flow cytometry tell me about my patient’s specimen?²

What does PARR tell me about my patient’s specimen?

How can I help to advance precision medicine?

What are ImpriMed’s prices?

References